Sutendra, G.: search on Z-Library

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1

Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer

Sutendra, G, Dromparis, P, Kinnaird, A, Stenson, T H, Haromy, A, Parker, J M R, McMurtry, M S, Michelakis, E D

Journal:

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

2

Sirtuin 3 Deficiency Is Associated with Inhibited Mitochondrial Function and Pulmonary Arterial Hypertension in Rodents and Humans

Paulin, Roxane, Dromparis, Peter, Sutendra, Gopinath, Gurtu, Vikram, Zervopoulos, Sotirios, Bowers, Lyndsay, Haromy, Alois, Webster, Linda, Provencher, Steeve, Bonnet, Sebastien, Michelakis, Evangelos

Journal:

Cell Metabolism

Year:

2014

Language:

english

File:

PDF, 3.79 MB

english, 2014

3

A Nuclear Pyruvate Dehydrogenase Complex Is Important for the Generation of Acetyl-CoA and Histone Acetylation

Sutendra, Gopinath, Kinnaird, Adam, Dromparis, Peter, Paulin, Roxane, Stenson, Trevor H., Haromy, Alois, Hashimoto, Kyoko, Zhang, Nancy, Flaim, Eric, Michelakis, Evangelos D.

Journal:

Year:

2014

Language:

english

File:

PDF, 4.08 MB

english, 2014

4

Pioglitazone inhibits HIF-1α-dependent angiogenesis in rats by paracrine and direct effects on endothelial cells

Dromparis, Peter, Sutendra, Gopinath, Paulin, Roxane, Proctor, Spencer, Michelakis, Evangelos D., McMurtry, M. Sean

Journal:

Journal of Molecular Medicine

Year:

2014

Language:

english

File:

PDF, 827 KB

english, 2014

5

The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted

Bonnet, S., Rochefort, G., Sutendra, G., Archer, S. L., Haromy, A., Webster, L., Hashimoto, K., Bonnet, S. N., Michelakis, E. D.

Journal:

Proceedings of the National Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 1.31 MB

english, 2007

6

Attenuating Endoplasmic Reticulum Stress as a Novel Therapeutic Strategy in Pulmonary Hypertension

Dromparis, P., Paulin, R., Stenson, T. H., Haromy, A., Sutendra, G., Michelakis, E. D.

Journal:

Year:

2013

Language:

english

File:

PDF, 24.38 MB

english, 2013

7

The impact of current and novel anti-diabetic therapies on cardiovascular risk

Ussher, John R, Sutendra, Gopinath, Jaswal, Jagdip S

Journal:

Future Cardiology

Year:

2012

Language:

english

File:

PDF, 1.34 MB

english, 2012

8

Hypoxia Inducible Factor 1α-Driven Vascular Endothelial Growth Factor and Stromal Derived Factor-1 Signaling Are Maintained in the Hypertrophied Right Ventricle in Congenital Heart Disease: Implications for Pulmonary Hypertension

Dromparis, P., Sutendra, G., Paulin, R., Zhao, J., Sandha, J., Rebeyka, I.M., Ross, D.B., Michelakis, E.D., Nagendran, J.

Journal:

The Journal of Heart and Lung Transplantation

Year:

2013

Language:

english

File:

PDF, 390 KB

english, 2013

9

MP60-14 THE VON HIPPEL LINDAU (VHL) TUMOR SUPPRESSOR INHIBITS P53 TARGET GENE EXPRESSION TO PROMOTE APOPTOSIS-RESISTANCE IN CANCER

Kinnaird, Adam, Dromparis, Peter, Boukouris, Aristeidis, Gurtu, Vikram, Saleme, Bruno, Zervopoulos, Sotirios, Sutendra, Gopinath, Michelakis, Evangelos

Journal:

The Journal of Urology

Year:

2017

Language:

english

File:

PDF, 273 KB

english, 2017

10

[American Thoracic Society American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California - ()] C27. RIGHT VENTRICULAR FUNCTION AND EXERCISE - Endothelin Receptor Inhibitors Decrease Contractility in the Hypertrophied Right Ventricle.

Nagendran, J, Sutendra, G, Haromy, A, Fu, DZ, Ross, DB, Rebeyka, IM, Michelakis, ED

Year:

2009

Language:

english

File:

PDF, 117 KB

english, 2009

11

Breast cancer diagnosis is associated with relative left ventricular hypertrophy and elevated endothelin-1 signaling

Maayah, Zaid H., Takahara, Shingo, Alam, Abrar S., Ferdaoussi, Mourad, Sutendra, Gopinath, El-Kadi, Ayman O. S., Mackey, John R., Pituskin, Edith, Paterson, D. Ian, Dyck, Jason R. B.

Journal:

Year:

2020

File:

PDF, 1.55 MB

2020

12

Observation of dislocations in melt grown potassium chloride crystals using thermal etching

P.G. Deo, Sutendra Kumar

Journal:

Journal of Crystal Growth

Year:

1968

Language:

english

File:

PDF, 971 KB

english, 1968

13

Ser-796 of β-galactosidase (Escherichia coli) plays a key role in maintaining a balance between the opened and closed conformations of the catalytically important active site loop

Larisa J. Jancewicz, Robert W. Wheatley, Gopinath Sutendra, Michael Lee, Marie E. Fraser, Reuben E. Huber

Journal:

Archives of Biochemistry and Biophysics

Year:

2012

Language:

english

File:

PDF, 2.23 MB

english, 2012

14

Endothelin Axis Is Upregulated in Human and Rat Right Ventricular Hypertrophy

Nagendran, J., Sutendra, G., Paterson, I., Champion, H. C., Webster, L., Chiu, B., Haromy, A., Rebeyka, I. M., Ross, D. B., Michelakis, E. D.

Journal:

Circulation Research

Year:

2013

Language:

english

File:

PDF, 3.02 MB

english, 2013

15

Fatty Acid Oxidation and Malonyl-CoA Decarboxylase in the Vascular Remodeling of Pulmonary Hypertension

Sutendra, G., Bonnet, S., Rochefort, G., Haromy, A., Folmes, K. D., Lopaschuk, G. D., Dyck, J. R. B., Michelakis, E. D.

Journal:

Science Translational Medicine

Year:

2010

Language:

english

File:

PDF, 5.47 MB

english, 2010

16

Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension

Gopinath Sutendra, Peter Dromparis, Sébastien Bonnet, Alois Haromy, Michael S. McMurtry, R. Chris Bleackley, Evangelos D. Michelakis

Journal:

Journal of Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 1.08 MB

english, 2011

17

A metabolic remodeling in right ventricular hypertrophy is associated with decreased angiogenesis and a transition from a compensated to a decompensated state in pulmonary hypertension

Gopinath Sutendra, Peter Dromparis, Roxane Paulin…

Journal:

Journal of Molecular Medicine

Year:

2013

Language:

english

File:

PDF, 1.00 MB

english, 2013

18

The Metabolic Basis of Pulmonary Arterial Hypertension

Sutendra, Gopinath, Michelakis, Evangelos D.

Journal:

Cell Metabolism

Year:

2014

Language:

english

File:

PDF, 3.03 MB

english, 2014

19

iASPP, a previously unidentified regulator of desmosomes, prevents arrhythmogenic right ventricular cardiomyopathy (ARVC)-induced sudden death

Notari, Mario, Hu, Ying, Sutendra, Gopinath, Dedeić, Zinaida, Lu, Min, Dupays, Laurent, Yavari, Arash, Carr, Carolyn A., Zhong, Shan, Opel, Aaisha, Tinker, Andrew, Clarke, Kieran, Watkins, Hugh, Fergu

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 2.29 MB

english, 2015

20

The Iron Paradigm of Pulmonary Arterial Hypertension: Popeye Knows Best

Sutendra, G., Bonnet, S.

Journal:

Circulation Research

Year:

2015

Language:

english

File:

PDF, 580 KB

english, 2015

21

Pulmonary Arterial Hypertension: Challenges in Translational Research and a Vision for Change

Sutendra, G., Michelakis, E. D.

Journal:

Science Translational Medicine

Year:

2013

Language:

english

File:

PDF, 2.58 MB

english, 2013

22

The antianginal ranolazine mitigates obesity-induced nonalcoholic fatty liver disease and increases hepatic pyruvate dehydrogenase activity

Batran, Rami Al, Gopal, Keshav, Aburasayn, Hanin, Eshreif, Amina, Almutairi, Malak, Greenwell, Amanda A., Campbell, Scott A., Saleme, Bruno, Court, Emily A., Eaton, Farah, Light, Peter E., Sutendra, G

Journal:

Year:

2019

Language:

english

File:

PDF, 2.18 MB

english, 2019

23

[Current Topics in Membranes] Free Radical Effects on Membranes Volume 61 || Chapter 5 A Mitochondria-AOS-Kv Channel Axis in Health and Disease; New Insights and Therapeutic Targets for Vascular Disease and Cancer

Sutendra, Gopinath

Year:

2008

Language:

english

File:

PDF, 654 KB

english, 2008

24

A Similar Metabolic Profile Between the Failing Myocardium and Tumor Could Provide Alternative Therapeutic Targets in Chemotherapy-Induced Cardiotoxicity

Saleme, Bruno, Sutendra, Gopinath

Journal:

Frontiers in Cardiovascular Medicine

Year:

2018

Language:

english

File:

PDF, 746 KB

english, 2018

25

Pyruvate dehydrogenase kinase as a novel therapeutic target in oncology

Sutendra, Gopinath, Michelakis, Evangelos D.

Journal:

Frontiers in Oncology

Year:

2013

Language:

english

File:

PDF, 1.12 MB

english, 2013

26

Metabolic Modulation of Clear-cell Renal Cell Carcinoma with Dichloroacetate, an Inhibitor of Pyruvate Dehydrogenase Kinase

Kinnaird, Adam, Dromparis, Peter, Saleme, Bruno, Gurtu, Vikram, Watson, Kristalee, Paulin, Roxane, Zervopoulos, Sotirios, Stenson, Trevor, Sutendra, Gopinath, Pink, Desmond B., Carmine-Simmen, Katia,

Journal:

European Urology

Year:

2016

Language:

english

File:

PDF, 2.79 MB

english, 2016

27

[American Thoracic Society American Thoracic Society 2009 International Conference, May 15-20, 2009 â¢ San Diego, California - ()] A106. ROLE OF INFLAMMATION IN PULMONARY VASCULAR REMODELING AND INJURY - A Primary Role of Activated CD8+ T-Cells in the Pathogenesis of Pulmonary Arterial Hypertension.

Sutendra, G, Bonnet, S, Dromparis, P, McMurtry, S, Haromy, A, Bleackley, C, Michelakis, ED

Year:

2009

File:

PDF, 146 KB

2009

28

β-Galactosidase (Escherichia coli) has a second catalytically important Mg2+ site

Gopinath Sutendra, Sean Wong, Marie E. Fraser, Reuben E. Huber

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 163 KB

english, 2007

29

297 DICHLOROACETATE IS A NOVEL THERAPY FOR RENAL CELL CARCINOMA

Kinnaird, Adam, Dromparis, Peter, Haromy, Alois, Bowers, Lyndsay, Hashimoto, Kyoko, Sutendra, Gopinath, Michelakis, Evangelos

Journal:

The Journal of Urology

Year:

2012

Language:

english

File:

PDF, 59 KB

english, 2012

30

The role of mitochondria in pulmonary vascular remodeling

Peter Dromparis, Gopinath Sutendra, Evangelos D. Michelakis

Journal:

Journal of Molecular Medicine

Year:

2010

Language:

english

File:

PDF, 513 KB

english, 2010

31

Uncoupling Protein 2 Deficiency Mimics the Effects of Hypoxia and Endoplasmic Reticulum Stress on Mitochondria and Triggers Pseudohypoxic Pulmonary Vascular Remodeling and Pulmonary Hypertension

Dromparis, P., Paulin, R., Sutendra, G., Qi, A. C., Bonnet, S., Michelakis, E. D.

Journal:

Circulation Research

Year:

2013

Language:

english

File:

PDF, 16.21 MB

english, 2013

32

Interaction with p53 explains a pro-proliferative function for VHL in cancer

Kinnaird, Adam, Boukouris, Aristeidis E., Saleme, Bruno, Dromparis, Peter, Zervopoulos, Sotirios D., Gurtu, Vikram, Sutendra, Gopinath, Michelakis, Evangelos D.

Journal:

Journal of Molecular Medicine

Year:

2020

File:

PDF, 2.33 MB

2020

33

Dehydroepiandrosterone Reverses Systemic Vascular Remodeling Through the Inhibition of the Akt/GSK3- /NFAT Axis

Bonnet, S., Paulin, R., Sutendra, G., Dromparis, P., Roy, M., Watson, K. O., Nagendran, J., Haromy, A., Dyck, J. R. B., Michelakis, E. D.

Journal:

Year:

2009

Language:

english

File:

PDF, 4.14 MB

english, 2009

34

The chicken embryo as a model for ductus arteriosus developmental biology: cracking into new territory

Sutendra, G., Michelakis, E. D.

Journal:

AJP Regulatory Integrative and Comparative Physiology

Year:

2006

Language:

english

File:

PDF, 200 KB

english, 2006

35

A miR-208-Mef2 Axis Drives the Decompensation of Right Ventricular Function in Pulmonary Hypertension

Paulin, R., Sutendra, G., Gurtu, V., Dromparis, P., Haromy, A., Provencher, S., Bonnet, S., Michelakis, E. D.

Journal:

Circulation Research

Year:

2015

Language:

english

File:

PDF, 7.13 MB

english, 2015

36

FoxO1 regulates myocardial glucose oxidation rates via transcriptional control of pyruvate dehydrogenase kinase 4 expression

Gopal, Keshav, Saleme, Bruno, Al Batran, Rami, Aburasayn, Hanin, Eshreif, Amina, Ho, Kim L, Ma, Wayne K, Almutairi, Malak, Eaton, Farah, Gandhi, Manoj, Park, Edwards A, Sutendra, Gopinath, Ussher, Joh

Journal:

American Journal of Physiology - Heart and Circulatory Physiology

Year:

2017

Language:

english

File:

PDF, 993 KB

english, 2017

37

p53âMediated Repression of the PGC1A (PPARG Coactivator 1Î±) and APLNR (Apelin Receptor) Signaling Pathways Limits Fatty Acid Oxidation Energetics: Implications for Cardioâoncology

Saleme, Bruno, Das, Subhash K., Zhang, Yongneng, Boukouris, Aristeidis E., Lorenzana Carrillo, Maria Areli, Jovel, Juan, Wagg, Cory S., Lopaschuk, Gary D., Michelakis, Evangelos D., Sutendra, Gopinath

Journal:

Journal of the American Heart Association

Year:

2020

File:

PDF, 1.11 MB

2020

38

[American Thoracic Society American Thoracic Society 2009 International Conference, May 15-20, 2009 â¢ San Diego, California - ()] C95. PULMONARY ARTERIAL HYPERTENSION: THE IDEAS KEEP COMING - A Novel Role of Nogo in Pulmonary Arterial Hypertension.

Sutendra, G, Bonnet, S, Wright, P, Dromparis, P, Haromy, A, Sessa, WC, Michelakis, ED

Year:

2009

File:

PDF, 147 KB

2009

39

410 Patients With Congenital Heart Disease Have Compensated Right Ventricular Hypertrophy (RVH) from Sustained Increased Levels of Angiogenesis: Implications for Treatment of Acquired RVH

P. Dromparis, G. Sutendra, R. Paulin, J. Zhao, I.M. Rebeyka, D.B. Ross, E.D. Michelakis, J. Nagendran

Journal:

Canadian Journal of Cardiology

Year:

2012

Language:

english

File:

PDF, 112 KB

english, 2012

40

Metabolic Modulation of Glioblastoma with Dichloroacetate

Michelakis, E. D., Sutendra, G., Dromparis, P., Webster, L., Haromy, A., Niven, E., Maguire, C., Gammer, T. L., Mackey, J. R., Fulton, D., Abdulkarim, B., McMurtry, M. S., Petruk, K. C.

Journal:

Science Translational Medicine

Year:

2010

Language:

english

File:

PDF, 1.70 MB

english, 2010

41

The Role of Nogo and the Mitochondria-Endoplasmic Reticulum Unit in Pulmonary Hypertension

Sutendra, G., Dromparis, P., Wright, P., Bonnet, S., Haromy, A., Hao, Z., McMurtry, M. S., Michalak, M., Vance, J. E., Sessa, W. C., Michelakis, E. D.

Journal:

Science Translational Medicine

Year:

2011

Language:

english

File:

PDF, 1.53 MB

english, 2011

42

Oxygen Sensing in the Pulmonary Circulation

Sutendra, Gopinath, Michelakis, Evangelos D.

Journal:

Circulation Research

Year:

2017

Language:

english

File:

PDF, 284 KB

english, 2017

43

Cell autonomous role of iASPP deficiency in causing cardiocutaneous disorders

Dedeić, Zinaida, Sutendra, Gopinath, Hu, Ying, Chung, Kathryn, Slee, Elizabeth A., White, Michael J., Zhou, Felix Y., Goldin, Robert D., Ferguson, David J. P., McAndrew, Debra, Schneider, Jurgen E., L

Journal:

Cell Death & Differentiation

Year:

2018

Language:

english

File:

PDF, 4.68 MB

english, 2018

44

356 Pyruvate Dehydrogenase Kinase 2 Controls Vascular Remodeling

T. Deuse, X. Hua, F. Länger, T. Gossler, M. Stubbendorff, A. Rakovic, C. Klein, G. Sutendra, P. Dromparis, L. Maegdefessel, P.S. Tsao, J. Velden, H. Reichenspurner, R.C. Robbins, F. Haddad, E. Michela

Journal:

The Journal of Heart and Lung Transplantation

Year:

2012

Language:

english

File:

PDF, 347 KB

english, 2012

45

The antianginal ranolazine mitigates obesity-induced nonalcoholic fatty liver disease and increases hepatic pyruvate dehydrogenase activity

Batran, Rami Al, Gopal, Keshav, Aburasayn, Hanin, Eshreif, Amina, Almutairi, Malak, Greenwell, Amanda A., Campbell, Scott A., Saleme, Bruno, Court, Emily A., Eaton, Farah, Light, Peter E., Sutendra, G

Journal:

Year:

2019

File:

PDF, 2.18 MB

2019

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